I'm not entirely sure what it is, but I've never much cared for this film. Perhaps it's the stupid comedy that pops up every now and again. Perhaps it's due the the last thirty minutes, none of which I care for (from the authorities to the store-owners, to the karate kid, etc.). Something's just off with this movie, as far as I'm concerned.
Some of the scenes are decent, but most of the characters are atrocious, including the aforementioned authorities and particularly the party-loving cop (which was another element I thought was more than a bit idiotic). Few of the actions in the second half of the movie are logical, and it grew increasingly hard to care for characters who were so stupid. This movie just rubs me the wrong way.
Part of it might be the fact that the idea in itself is pretty cool - seeing a bunch of people slowly realize that there's a disease in the area that's highly contagious and they die slowly to it could be a really well-done psychological and serious horror film. But that's not the direction that they took.
Instead they threw in humor that, for the most part, didn't work (the ending scene with the black individuals being a case in point) and far from taking a serious, psychological look at how each character is affected by the knowledge of their mortality, we get subplots that make little sense and authorities who, for some unexplained reason, don't mind if a disease spreads throughout their community. Eli Roth had a hit with Hostel, but it's a shame his earlier hit misses the mark. Points for Karen (Jordan Ladd) being so cute, at least before her flesh got eaten off.